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BRCA1 affects lipid synthesis through its interaction with acetyl-CoA
carboxylase.
Journal Of Biological Chemistry
281(6)
3172-81
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Inhibition of BRCA1 in breast cell lines causes the centrosome
duplication cycle to be disconnected from the cell cycle.
Oncogene
25(2)
298-303
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PMID 16738325.
An ATR- and BRCA1-mediated Fanconi anemia pathway is required for
activating the G2/M checkpoint and DNA damage repair upon
rereplication.
Molecular And Cellular Biology
26(12)
4601-11
(2006)
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PMID 16782705.
BRCA1 interacts with poly(A)-binding protein: implication of BRCA1 in
translation regulation.
Journal Of Biological Chemistry
281(34)
24236-46
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PMID 16357170.
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.
Cancer Research
65(24)
11597-604
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PMID 15967981.
Depletion of BRCA1 impairs differentiation but enhances proliferation
of mammary epithelial cells.
Proceedings Of The National Academy Of Sciences Of The United States Of
America
102(26)
9176-81
(2005)
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PMID 15520196.
BRCA1 induces antioxidant gene expression and resistance to oxidative
stress.
Cancer Research
64(21)
7893-909
(2004)
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PMID 14534301.
Detection of protein folding defects caused by BRCA1-BRCT truncation
and missense mutations.
Journal Of Biological Chemistry
278(52)
53007-16
(2003)
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PMID 12717416.
Role of BRCA1 in cellular resistance to paclitaxel and ionizing
radiation in an ovarian cancer cell line carrying a defective BRCA1.
Oncogene
22(16)
2396-404
(2003)
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PMID 12527903.
Role of BRCA1 in heat shock response.
Oncogene
22(1)
10-27.
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PMID 12400015.
Direct interaction between BRCA1 and the estrogen receptor regulates
vascular endothelial growth factor (VEGF) transcription and secretion
in breast cancer cells.
Oncogene
21(50)
7730-9.
(2002)
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PMID 11239959.
Chromosomal instability in BRCA1- or BRCA2-defective human cancer cells
detected by spontaneous micronucleus assay.
Mutation Research
474(1)
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PMID 11257228.
The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage
and tumor suppression.
Cell
104(5)
743-53.
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PMID 11163768.
Constitutive activation of JAK-STAT3 signaling by BRCA1 in human
prostate cancer cells.
Febs Letters
488(3)
179-184.
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PMID 11301010.
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and
contributes to its DNA repair function.
Cell
105(1)
149-60.
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PMID 11278247.
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a
breast cancer-derived mutation.
Journal Of Biological Chemistry
276(18)
14537-40.
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PMID 11053450.
Characterization of tumor-associated Chk2 mutations.
Journal Of Biological Chemistry
276(4)
2971-4
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Involvement of Brca1 in S-phase and G(2)-phase checkpoints after
ionizing irradiation.
Molecular And Cellular Biology
21(10)
3445-50.
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PMID 11447276.
Deficiency of human BRCA2 leads to impaired homologous recombination
but maintains normal nonhomologous end joining.
Proceedings Of The National Academy Of Sciences Of The United States Of
America
98(15)
8644-9.
(2001)
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PMID 11090615.
Sequence-specific transcriptional corepressor function for BRCA1
through a novel zinc finger protein, ZBRK1.
Mol Cell
6(4)
757-68
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PMID 10938285.
BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer
cell lines.
Journal Of Biological Chemistry
275(43)
33487-96
(2000)
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PMID 10660629.
Regulation of BRCA1 expression by the Rb-E2F pathway.
Journal Of Biological Chemistry
275(6)
4532-6.
(2000)
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PMID 10910365.
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA
damage response.
Nature
406(6792)
210-5
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PMID 10783165.
BASC, a super complex of BRCA1-associated proteins involved in the
recognition and repair of aberrant DNA structures.
Genes And Development
14(8)
927-39.
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PMID 10943845.
BRCA1 is associated with a human SWI/SNF-related complex: linking
chromatin remodeling to breast cancer.
Cell
102(2)
257-65
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PMID 11016951.
Increase of androgen-induced cell death and androgen receptor
transactivation by BRCA1 in prostate cancer cells.
Proceedings Of The National Academy Of Sciences Of The United States Of
America
97(21)
11256-61
(2000)
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PMID 11042697.
The anti-proliferative effects of 1alpha,25(OH)2D3 on breast and
prostate cancer cells are associated with induction of BRCA1 gene
expression.
Oncogene
19(44)
5091-7
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PMID 10644742.
BRCA1 effects on the cell cycle and the DNA damage response are linked
to altered gene expression.
Journal Of Biological Chemistry
275(4)
2777-85.
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PMID 10435628.
BRCA1 expression during prenatal development of the human mammary
gland.
Oncogene
18(27)
4039-43
(1999)
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PMID 10635334.
Genetic analysis of BRCA1 function in a defined tumor cell line.
Mol Cell
4(6)
1093-9
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Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA
damage response.
Science
285(5428)
747-50
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PMID 10334989.
BRCA1 inhibition of estrogen receptor signaling in transfected cells.
Science
284(5418)
1354-6
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PMID 10373498.
BRCA1 expression restores radiation resistance in BRCA1-defective
cancer cells through enhancement of transcription-coupled DNA repair.
Journal Of Biological Chemistry
274(26)
18808-12.
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PMID 9662397.
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via
RNA helicase A.
Nature Genetics
19(3)
254-6
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PMID 9703501.
BRCA1 required for transcription-coupled repair of oxidative DNA
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Science
281(5379)
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