Site Report - HS$CDKN1B_01 - CDKN1B (cyclin-dependent kinase inhibitor 1B (p27, Kip1))

R18755	Site: HS$CDKN1B_01 - CDKN1B (cyclin-dependent kinase inhibitor 1B (p27, Kip1))

Binding Site Information [hide]

Identifier	HS$CDKN1B_01
Gene	Human CDKN1B (cyclin-dependent kinase inhibitor 1B (p27, Kip1))
Region	promoter
Sequence
Export
Sequence Type	DNA
Reference Point for Sequence Start
Element
Element Range	from -714 to -680
External Identifiers
Element Mapped to Promoter(s)
Binding Factors	BRCA1(h ) Quality:6
Factor Source	rec(human-MCF7); Human; recombinant expression: coding sequence of human factor has been expressed in human breast adenomcarcinoma cell line; a telomerase-positive cell line; immortalized
Method	functional analysis
Comments	region -714 to -680 is 100% identical to the mouse promoter ; no sequence is given in reference [1]

References [hide]

(1 entry)

[1] PMID 12082635 . Williamson, E. A., Dadmanesh, F., Koeffler, H. P. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene 21(20) 3199-206. (2002)