How to Interpret Disease Mutation Data Webinar
Learn how to save time in finding pathological mutations reported in the scientific literature. This webinar provides a live presentation of the Human Gene Mutation Database, HGMD® and Alamut® – Mutation Interpretation Software. We will detail the application examples and demonstrate the basics of getting started with the HGMD® database and the Alamut® software. Learn about: Read More
Webinar: Analysis of TAL1 ChIP-seq Intervals
April 26, 2012
10:00 am EST
Challenges of Transcription Factor Binding Site Prediction
Transcription factors are recognized as important components of signaling cascades controlling all types of normal cellular processes as well as response to external stimulus, conditions of disease, drug treatment, and more. However, comparatively few known transcription factor binding sites have been experimentally characterized relative to the total number of binding sites expected. This large gap Read More
Next Generation Sequencing in Clinical Research “Results and Lessons Learned”
Today BioPharma users leverage the power of Genome Trax to identify human genome variations of functional significance by mapping their NGS data to known elements such as disease mutations and regulatory sites. This webinar with Dr. Andreas Kremer from ERASMUS Medical Center, discusses the next generation sequencing data analysis tool and how Genome Trax is able to Read More
Strategies for Drug Target Identification
Most drug target identification strategies result in a list of target genes. While there are a number of basic challenges that are shared by all drug target mining approaches due to the complexity of biological signaling networks, non-nucleic acid approaches require particularly detailed information about molecular functions, pathways and phenotypes of the gene products. This Read More
Understanding Diseases and Pathways through NGS Data Analysis
Human disease has long been a subject of personal and intense interest, both to researchers and the population in general. In recent decades many studies have focused on the mutated genes and affected pathways that underlie mechanisms of disease. Next generation sequencing now enables us to take a closer look at the mutations causing inherited Read More
Electronic Resources for Librarians
You know the pitfalls of relying on PubMed for topic-specific literature searches – which is why you subscribe to library databases such as Web of Science for use by the faculty, students, and staff within your university community. However, many traditional library databases are limited to citation indexes which provide as search results a list Read More