CLC bio and BIOBASE integrates genome informatics framework with Genome Trax database
Providence, RI, USA — September 27, 2011 — At the “Evolution of Next-Gen Sequencing” (NGx) conference in Providence, Rhode Island, CLC bio and BIOBASE launched a new plugin for CLC bio’s new framework for visualizing, combining and analyzing genome data, Genomics Gateway, which integrates the human curated biological databases contained in BIOBASE’s Genome Trax™, including Read More
Data sharing in the life sciences – Part I
What is the best way to create, share and maintain biological databases? This is a question our COO, Frank Schacherer, has blogged about on his own website. Over a series of posts, we’ll reproduce his thoughts here with permission. Frank writes: “If nature has made any one thing less susceptible than all others of exclusive Read More
Beyond Next Generation Sequencing – A report from the BNGS workshop at the Renyi Institute in Hungary
NGS technologies have revolutionized the speed and detail with which scientists acquire genomic and transcriptomic information, while requiring only a fraction of the cost of classical sequencing strategies – opening up novel research possibilities in many areas including cancer research, gene regulation, epigenetics, personalized medicine and pharmacogenomics. As many of us know, such advancements in Read More
G over C Mutation Bias in Human Genetic Disease Helps in Clinical Scoring of Causative Mutations
When double or multiple de novo point mutations are encountered in a molecular diagnostic screen for a monogenic disease, are there any quick techniques for identifying which is more likely to be the causative mutation? According to a recent study published by Xiao et al, the answer is yes – if the point mutations involve Read More