Providence, RI, USA — September 27, 2011 — At the “Evolution of Next-Gen Sequencing” (NGx) conference in Providence, Rhode Island, CLC bio and BIOBASE launched a new plugin for CLC bio’s new framework for visualizing, combining and analyzing genome data, Genomics Gateway, which integrates the human curated biological databases contained in BIOBASE’s Genome Trax™, including TRANSFAC® and HGMD® Professional.
COO at BIOBASE, Dr. Frank Schacherer, states, “Genomics Gateway from CLC bio is a powerful solution to implement a track-based view of our databases, which not only makes it easy to filter down the results, but it also eliminates the need to build your own scripts for this type of work. We’re confident researchers will find the combination of an integrated and intuitive solution to advanced analyses combined with expert-curated biological databases, very valuable.”
Bioinformatics Specialist at CLC bio, Dr. Anika Joecker, adds, “For example in an re-sequencing workflow, once you have done your mapping, read removal, SNP/DIP detection, and structural variation detection, you’re typically looking for the interesting, disease related mutations. The plugin adds several tracks to a Genomics Gateway trackset, for instance a track for variations found in inherited diseases (HGMD database) and one track for gene-disease relations. Based on that you can filter down your variations to the genes which are probably causing the disease Straightforward, yet very powerful!”
Genome Trax license holders have access to the data in BIOBASE’s online databases, including 3,000+ regulatory sites from TRANSFAC®, 80,000+ disease linked mutations from HGMD® Professional, 600,000+ ChIP-Seq fragments with best binding site predictions, Post Translational Modifications (PTMs), and Transcription Start Sites (TSSs). The plugin that integrates these expert-curated biological databases with CLC bio’s award-winning platform is free.
CLC bio’s Genomixs Gateway focuses on comparative filtering of genomic variations, giving scientists a fast and easy way to do functional classification and filtering of SNPs or other kind of genomic variations, using multiple data sources, including external public databases. This framework offers users a fast and easy way to do further downstream analyses and to combine them with existing knowledge.
About BIOBASE
http://www.biobase-international.com
About CLC bio