Most drug target identification strategies result in a list of target genes.  While there are a number of basic challenges that are shared by all drug target mining approaches due to the complexity of biological signaling networks, non-nucleic acid approaches require particularly detailed information about molecular functions, pathways and phenotypes of the gene products.

Join our FREE webinar where we discuss how the complexities of post-translational modification, recycling/degradation, and alternative splicing patterns of proteins affect signaling networks in ways that can impact the selection of drug targets. Using examples of proteins involved in alzheimers, epilepsy and other diseases, we will demonstrate how the use of biological databases describing inherited mutations (HGMD®) and the molecular mechanisms of signaling events (PROTEOME™) make it easier to prioritize and filter potential drug targets than relying on literature searches alone.

Learn how to:

• Identify known mutations that affect sites of post-translational modification
• Visualize how key post-translational events affect characterized pathways
• Identify proteins which participate in multiple signaling networks

Who should attend:

Researchers who are interested in the identification or characterization of drug targets and who want to make more efficient use of the published literature to identify, prioritize and filter candidates. Genetic counselors and researchers who are interested in the functional consequences/downstream effects of disease causing mutations.

WHEN:

Thursday, February 2, 2012
4 PM Central European / 10 AM EST (Eastern Standard – US) / 7 AM PC (Pacific Standard – US)

REGISTER NOW! (Space is limited!)