BRENDA is a relational database of molecular and metabolic information.  It provides researchers of biochemistry and medicine a user-friendly navigation system offering access to a comprehensive summary of enzyme specific data.

The database includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. The database also provides additional information on ligands, which function as natural or in vitro substrates/products, inhibitors, activating compounds, cofactors, bound metals, etc.

Benefits

  • The ability to perform individual database queries based on your targets
  • Access to a human-readable database format allowing you to find data easier without advanced queries
  • The flexibility to integrate BRENDA’s relational database with your existing in-house data and resources
  • The security and privacy of a local installation behind your firewall
  • BRENDA Ligand provides a search for all included synonyms of a given compound and thus facilitates finding all enzyme-ligand-related information.  The ligand structures are provided in three formats (molfile, InChls, gif-pictures)
  • BRENDA Ligand Substructure Search provides chemical substructure searches for most of the small molecules functioning as ligands, using a molecular editor

Key Features

  • 83,000+ enzymes from 10,500 organisms
  • Data from 120,000+ publications
  • 1,200,000+ enzyme-ligand relationships are stored
  • 107,800+ structures of ligands
  • Genome Explorer includes an up to date set of 15,140 completely sequenced genomes

Spring 2013.1 release statistics

Access Options

Online
An online subscription provides access to the BRENDA web interface. Online subscriptions are available at the concurrent user and institution-wide level. All subscription levels require username/password authentication.

Download
A download subscription allows for a download of the complete BRENDA relational database and web interface. A download allows you to query and extract all fields of BRENDA data for integration into your own, or 3rd party, analysis pipelines and tools. However redistribution of, or public access to / display of, the data is not allowed without prior written consent. Relational download subscriptions are only available at the institution-wide level. MySQL platform is supported.

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