BIOBASE BRENDA Professional is the main collection of enzyme functional data available to the scientific community worldwide. The enzymes are classified according to the Enzyme Commission list of enzymes.
BRENDA Professional is maintained and developed at the Institute of Biochemistry and Bioinformatics at the Technical University of Braunschweig, Germany. Data on enzyme function are extracted directly from the primary literature by scientists holding a degree in Biology or Chemistry.
The database is built on a relational database of molecular and metabolic information. It provides researchers of biochemistry and medicine a user-friendly navigation system offering access to a comprehensive summary of enzyme specific data.
BRENDA Professional includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. The database also provides additional information on ligands, which function as natural or in vitro substrates/products, inhibitors, activating compounds, cofactors, bound metals, and other attributes.
BRENDA Professional includes the supplements FRENDA and AMENDA, extracted from about 20 million PubMed references, not available in the public version. FRENDA (Full Reference ENzyme DAta) aims at providing an exhaustive collection of literature references containing organism-specific enzyme information. It currently covers nearly 6 million enzyme/organism/reference combinations (nearly 400,000 enzyme/organism combinations). AMENDA (Automatic Mining of ENzyme DAta) contains a large amount of enzyme data, covering information on (sub)cellular localizations and source tissues.
|BRENDA Professional||BRENDA Public|
|Quick, Full-Advanced Text Search||Yes||Yes|
|Substructure and Sequence Search||Yes||Yes|
|Taxonomy, Genome, EC and Ontology Explorer||Yes||Yes|
|Relational database download||Yes||No|
|FRENDA and AMENDA supplement||Yes||No|