BIOBASE offers comprehensive solutions to life science researchers. Our databases contain unique, manually-curated data from peer-reviewed literature which our analysis tools leverage in order to bring meaning to, and generate maximum value from, your experimental data.

BIOBASE offers a broad and flexible range of solutions that can be customized to individual needs, including non-profit research institutes, academic labs, universities, and computational biologists in the life science industry.

Gene Regulation Analysis

TRANSFAC®

TRANSFAC®

TRANSFAC® is a unique knowledge-base containing published data on eukaryotic transcription factors and miRNAs, their experimentally-proven binding sites, and regulated genes. The extensive compilation of binding sites provides the most comprehensive data set of transcription factor – gene interactions available.  The same data also forms the basis of derived positional weight matrices which can be » Read More

Human Mutation & Variant Analysis

HGMD®

HGMD®

BIOBASE HGMD® Professional is a unique resource providing comprehensive data on human inherited disease mutations to genetics and genomic research. Its compilation enables quick access to both single mutation queries and advanced search applications. HGMD® is widely used in human genetics research, diagnostics, and personal genomics applications and was an essential tool in analyzing the » Read More

PGMD™

PGMD™

The PharmacoGenomic Mutation Database (PGMD™) BIOBASE PGMD™ is a resource for identifying all published genetic variants that have been shown to affect drug response in patients. We have mined the scientific literature for every in vivo patient study that has yielded a significant correlation between genotype and drug response, and offer multiple delivery models for » Read More

Genome Trax™

Genome Trax™

Genome Trax™ is a comprehensive compilation of variant knowledge that is made available for download for easy integration into your own custom variant analysis pipeline for human whole genome, exome and targeted sequences. With Genome Trax™ content you can confidently identify known pathogenic variants or explore novel, as-yet-uncharacterized variants found within your sequence samples that » Read More

ANNOVAR™

ANNOVAR™

High-throughput sequencing platforms are generating massive amounts of genetic variation data and it remains a challenge to pinpoint the small subset of functionally important variants within an individual genome or cohort of genomes.  ANNOVAR™, an efficient command line Perl program to functionally annotate genetic variants from high-throughput sequencing data, was developed to fill this need » Read More

POSSUMweb

Pictures Of Standard Syndromes and Undiagnosed Malformations POSSUMweb is a dysmorphology database of syndromes including multiple malformations, chromosomal abnormalities, skeletal dysplasias, and metabolic disorders. The easy to use web-based browser saves time and effort in researching and cross-referencing syndrome information. POSSUMweb provides quick access to  detailed syndrome commentaries and linked images including photos, Xrays, scans, diagrams » Read More

Enzymology

BRENDA

BIOBASE BRENDA Professional is the main collection of enzyme functional data available to the scientific community worldwide.  The enzymes are classified according to the Enzyme Commission list of enzymes. BRENDA Professional is maintained and developed at the Institute of Biochemistry and Bioinformatics at the Technical University of Braunschweig, Germany. Data on enzyme function are extracted » Read More