BIOBASE offers comprehensive solutions to life science researchers. Our databases contain unique, manually-curated data from peer-reviewed literature which our analysis tools leverage in order to bring meaning to, and generate maximum value from, your experimental data.

BIOBASE offers a broad and flexible range of solutions that can be customized to individual needs, including non-profit research institutes, academic labs, universities, and computational biologists in the life science industry.

Functional Analysis

PROTEOME™

PROTEOME™

BIOBASE PROTEOME is a knowledgebase containing data on genes and miRNAs, the diseases they are associated with, the drugs they are targeted by, and the pathways and networks they act within.  Based on its extensive compilation of published functional attributes, the powerful ontology search query system allows scientists to quickly find answers to questions relevant » Read More

Gene Regulation Analysis

TRANSFAC®

TRANSFAC®

TRANSFAC® is a unique knowledge-base containing published data on eukaryotic transcription factors and miRNAs, their experimentally-proven binding sites, and regulated genes. The extensive compilation of binding sites provides the most comprehensive data set of transcription factor – gene interactions available.  The same data also forms the basis of derived positional weight matrices which can be » Read More

ExPlain™

ExPlain™

BIOBASE ExPlain™ is a unique data analysis system that combines promoter and pathway analysis tools. Using the power of TRANSFAC®’s transcription factor binding site derived positional weight matrices, ExPlain™ enables you to identify transcription factors affecting gene expression in your microarray and RNA-Seq experiments, as well as predict how they, in combination, can induce observed » Read More

Annotation of Genetic Variants

ANNOVAR™

ANNOVAR™

BIOBASE ANNOVAR, functional annotation of genetic variants from high-throughput sequencing data, is an efficient command line Perl program to functionally annotate genetic variants from diverse genomes (including human genome hg18, hg19, as well as mouse, worm, fly, yeast and many others). High-throughput sequencing platforms are generating massive amounts of genetic variation data, and it remains » Read More

Pharmacogenomics Data

PGMD™

PGMD™

The PharmacoGenomic Mutation Database (PGMD™) BIOBASE PGMD™ is a resource for identifying all published genetic variants that have been shown to affect drug response in patients. We have mined the scientific literature for every in vivo patient study that has yielded a significant correlation between genotype and drug response, and offer multiple delivery models for » Read More

Human Mutation & Variant Analysis

HGMD®

HGMD®

BIOBASE HGMD® Professional is a unique resource providing comprehensive data on human inherited disease mutations to genetics and genomic research. Its compilation enables quick access to both single mutation queries and advanced search applications. HGMD® is widely used in human genetics research, diagnostics, and personal genomics applications and was an essential tool in analyzing the » Read More

Genome Trax™

Genome Trax™

BIOBASE Genome Trax™ is a comprehensive compilation of variant knowledge that allows you to quickly and confidently identify pathogenic variants in human whole genome or exome sequences. If you are analyzing whole genome or exome sequencing data — Genome Trax™ is the tool to use. Genome Trax™ makes it easy to upload a complete genome’s » Read More

Enzymology

BRENDA

BIOBASE BRENDA Professional is the main collection of enzyme functional data available to the scientific community worldwide.  The enzymes are classified according to the Enzyme Commission list of enzymes. BRENDA Professional is maintained and developed at the Institute of Biochemistry and Bioinformatics at the Technical University of Braunschweig, Germany. Data on enzyme function are extracted » Read More