BIOBASE offers comprehensive solutions to life science researchers. Our databases contain unique, manually-curated data from peer-reviewed literature which our analysis tools leverage in order to bring meaning to, and generate maximum value from, your experimental data.
BIOBASE offers a broad and flexible range of solutions that can be customized to individual needs, including non-profit research institutes, academic labs, universities, and computational biologists in the life science industry.
With 3-4 million variants identified per sequenced human genome, it can be difficult to determine the few that count. Genome Trax™ enables you to positively identify variants of functional significance by mapping the NGS data to known elements such as disease mutations and regulatory sites. It can also filter out common variants, identify novel mutations Read More
HGMD® Professional is a unique resource providing comprehensive data on human inherited disease mutations to genetics and genomic research. Its compilation enables quick access to both single mutation queries and advanced search applications. HGMD® is widely used in human genetics research, diagnostics, and personal genomics applications and was an essential tool in analyzing the genomes Read More
ExPlain™ is a unique data analysis system that combines promoter and pathway analysis tools. Using the power of TRANSFAC®’s transcription factor binding site derived positional weight matrices, ExPlain™ enables you to identify transcription factors affecting gene expression in your microarray and RNA-Seq experiments, as well as predict how they, in combination, can induce observed gene Read More
TRANSFAC® is a unique knowledge-base containing published data on eukaryotic transcription factors, their experimentally-proven binding sites, and regulated genes. Based on its broad compilation of binding sites, positional weight matrices are derived which can be used with the included Match™ tool to search DNA sequences for predicted transcription factor binding sites. Promoter analysis of high-throughput Read More
The powerful ontology search query system, with specialized tools for gene set analysis and pathway visualization, allows scientists working with mammalian, yeast, worm and plant species to quickly find answers to questions relevant to their research. A specialized custom sequence annotation tool allows scientists working with other species to extend predictive functions to newly sequenced Read More
BRENDA is a relational database of molecular and metabolic information. It provides researchers of biochemistry and medicine a user-friendly navigation system offering access to a comprehensive summary of enzyme specific data. The database includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. Read More
ANNOVAR, functional annotation of genetic variants from high-throughput sequencing data, is an efficient command line Perl program to functionally annotate genetic variants from diverse genomes (including human genome hg18, hg19, as well as mouse, worm, fly, yeast and many others). High-throughput sequencing platforms are generating massive amounts of genetic variation data, and it remains a Read More